Brand Impact and Popular Culture Essay Example | Topics and Well Written Essays - 1500 words

Brand Impact and Popular Culture - Essay Example This paper illustrates that Matthew McConaughey is an American actor well known for his role in films like Dazed and Confused  (1993), Amistad  (1997), and Failure to Launch (2006). In recent years, McConaughey has featured in small, independent films and has featured in some exigent roles. Toyota Corolla was launched in 1966 primarily as a family car. It was positioned as a progressive and friendly vehicle. The newest version of the Corolla is focused on providing an instantaneous good feeling to the customer. There is a picture of a sleek, attractive Toyota Corolla zooming along the river side on the first slide of the theme board. The photograph of a smiling, friendly brand endorser on the same slide is used to encode the feeling of goodness. The Brand Typology model suggests that brands can be classified into eight categories namely Clean Slates, Weak Brands, Little Tigers, Defenders, Olympic, Classic, Specialist and Fading Stars by analyzing their momentum and familiarity in the marketplace. Olympic brands are illustrious and have a large customer base. These brands are usually the talk of the town and serve as benchmarks for other brands. At present Toyota Corolla is an Olympic brand. The car was launched in 1966 and is now pegged as the ‘World’s Most Popular Car’. The Japanese company has manufactured more than 40 million Toyota Corolla cars since its launch. The model is sold in more than 150 countries and regions around the world. McConaughey too is recognized worldwide. The experienced actor has staged a remarkable mid-career comeback and his popularity has increased tremendously in recent times. Good looks, humility, and award-winning performances have made McConaughey an admirable person.

Design Methodology Essay Example for Free

Design Methodology Essay A design methodology is series of phases that guide a project lifecycle. Generally speaking there are an uncountable number of design methodologies, but the two most utilised are the predictive and the adaptive approach. The predicative approach assumes that a project can be planned in advance and the adaptive approach assumes the opposite. These design methodologies are also referred to as traditional or waterfall approach and spiral or iterative approach respectively. The phases involved generally fall into the categories of planning, analysis, design, implementation and support. Whether implementing the predictive or adaptive approach, each phase is an important step in the design methodology but can differ depending on the approach taken. Additional, depending on the design methodology implemented, the phases may not exist as separate entities and can be combined, split up or even removed all together. During the planning phase the problem and scope are defined, a work breakdown structure and schedule is developed, a feasibility study is undertaken, team members are assigned and official approval is sought for commencement. The analysis phase involves gathering information relevant to the scope of the problem, constructing models or prototypes to assist information gathering, defining the goals or requirements and assessing and prioritising those goals or requirements. Information gathering techniques involve interviews, observation, reviewing industry standards, questionnaires, joint application design (JAD) sessions and general research. The design phase includes designing and integrating the system controls, designing the system and designing the system interfaces. The implementation phase involves constructing the system, verifying and testing the system, data conversion, training users, documenting the system and installation of the system. Finally, the support phase encompasses maintenance of the system, improving the systems and providing continual support for users of the system. The traditional or waterfall approach follows a sequential set of phases that need to be complete in order, one after the other. In most cases the waterfall approach does not contain overlapping phases and each phase must be completed before beginning the next phase. On the other hand, the adaptive approach involves repeating phases and/or overlapping phases. Usually the phases are repeated in a looping or spiral fashion but can also follow the more traditional linear pattern with overlap or loopbacks to only a few of the phases. Design methodologies encompass not only how the project lifecycle is planned out but also the models, tools and techniques used to assist the project lifecycle. Models can include anything from diagrams and charts to real world representations and abstract representations. Tools range from simple programs to produce models to complex Computer Aided Software Engineering (CASE) tools. Finally, techniques consist of step-by-step instructions, guidelines or advice to assist the completion of the phases or the project lifecycle. Design methodologies are mostly notably applied to project management and technological industries such as software development. In project management, design methodologies allow projects to be directed to achieve the expected goals within the given constraints. Technological industries also follow a very similar approach to project management. Methodologies can also be applied to everyday tasks, especially within the area of business. In retail, staff are often given guidelines on how to deal with customer complaints. Most notably, ALARA involves the steps of acknowledge, listen, ask questions, recap and act. This is in essence a design methodology which begins with the planning phase (acknowledge), the analysis and design phase (listen and ask questions), the support phase (recap) and implementation phase (act).

The Computer’s Positive Impact on Education :: Teaching Learning Essays

The Computer’s Positive Impact on Education Once upon a time there was a teacher and a classroom full of bright and ambitious students. One day a bit of brand new technology was introduced into the classroom. This new technological tool was designed to enable teachers to save time and better instruct groups of students. Students would also be able to utilize this new tool for practicing math problems and spelling words. This new tool is also proven to be very easy to use to compose and edit information on it. In spite of all these wonderful qualities this new advanced technology can bring to the classroom, it was approached with much skepticism. In the early 1900’s, people were concerned and worried about the kinds of problems "the chalkboard" would bring to education! A century later, teacher across the country teachers and students are still successfully utilizing chalkboards in the classroom for teaching and learning. This little story is true and significantly compares to computers entering the education turf. I’m going to take this opportunity to expand on the positive contributions compu ters have and will make in the education field. Computers are having a positive affect on education in many ways. Some of the optimism about computers in education is due to the fact that computers offer diverse collections of resources, variations of media type, increased communications, as well as provision of a records management tool for teachers. The diversity of resources teachers and students have access to through the use of computers is phenomenal. Basically, software and the Internet are the methods used to obtain access to overwhelming amounts of data. The information may be in the form of written material, audio material, games, user-interaction, animation and many more. The Teacher Resource Center (TRC) in Indiana maintains an updated website of teacher resources at "www-ed.fnal.gov/programs/ed_mat_trc.html". Software provides age-appropriate instructional design in the math and science disciplines, as well as in language arts and social studies. Many of these are interactive and/or re-create models of items ranging from complex graphs, historical events, to science experiment labs. Reference libraries are also available on software. There are complete electronic encyclopedia software with color graphics and audio. Information can be printed out, which is convenient for students who are conducting research. Another software area relating to the educational field is pre-school software. Pre-schoolers use computers for "coloring/painting", playing memory games and learning basic letters, numbers, shapes etc.

Deaf Like Me Book Report Essay

This book was really interesting and touching. The parents of Lynn, the deaf little girl, were very strong parents and their struggle to be able to make their daughters life as normal as possible was hard for them since everywhere they went the answer the always got was, for Lynn to try to talk and be treated as a normal child. As parents, Louise and Tom did everything they were told and only hoped for the best and that one day their deaf child would be able to talk. Since the beginning when they found out their daughter was deaf they did all the research they could to try and be able to make life better for Lynn. Every doctor and specialist they saw always told me to treat her as a normal child, to talk to her, and to not use gestures or sign language. When Louise and Tom took Lynn to get tested at several different places they finally found that she was profoundly deaf. They got her a hearing aid to see if this would help her hear better but sadly it didn’t make a difference, Lynn still wasn’t able to hear anything. The things the doctors and specialist told them stuck in their heads; if she did gestures or used signs to communicate she would not have a normal life and be labeled as a deaf person. The way they described this made Louise and Tom think that if their daughter didn’t learn how to speak or read lips she would have a miserable life. They didn’t want Lynn to suffer when she got older they wanted her to grow up like any other child and be able to communicate with others and talk. Lynn wasn’t retarded or handicapped, she was just deaf but because of the information they got it seemed like she was and that was what they didn’t want her to be labeled as. When they heard about Star King Exceptional School, which was a school for deaf children, they wanted to see if this was a good place for Lynn to attend. This school was an oral school only and kids there were thought how to read lips and learn how to talk. Since they had heard a lot of good things about this school and the way it was described to them they thought this would be the perfect place for Lynn to learn how to talk. Lynn attended here but throughout the whole time she was there she only made a little progress. With practicing at home and at school Louise and Tom knew that she  would eventually learn how to talk because she made small progress and was slowly learning. Like I mentioned the information they were told repeatedly was only half the truth. When they met Barbara Simmons at the meeting they had at the school their lives would finally become less stressful. She thought sign language was a good way to communicate with deaf children and by them learning sign language it would make their lives easier. She introduced them to Jim and Alice Hudson, a deaf couple, and they talked to them about how sign language would help Lynn to do better in life and how in reality she would probably not be able to talk and read lips perfectly. After talking to them and reading the articles they had gave them Louise and Tom were willing to try it and take the chance. Using sign language was a success and they were able to communicate with Lynn very fast and within a week they were able to understand each other. This was a way faster progress than before. They finally decided to use sign language and Lynn’s progress got better and better and sign language because their new second language. While reading the book I learned a lot and it made me think and wonder why they would put young children through so much struggle just because they don’t want them to use sign language. Every time I came across the comments they made about her not being a â€Å"normal child† if she didn’t learn how to speak really upset me because just because she was deaf it didn’t mean she wasn’t going to be able to do things like everyone else. It’s sad how they were never able to communicate with her and the way the struggle could have been avoided. Lynn was a bright child she learned how to read lips very quickly so I’m pretty sure if she had started to learn sign language when she was two-years old she would have picked it up quickly too. Several incidents that happened in the story were very interesting like when Lynn was able to say â€Å"Blue† after touching her father’s chest and then hers. This I didn’t even know it was going to work but it did. When Mr. Hughes went up to talk at the meeting and was saying nothing but negative stuff about sign language it bothered me because he should want to try something that was better for his son and for him. Also when Tom was in the room with Sandra, Mike, Jim and Alice and they were signing he felt like he was the odd ball because he couldn’t understand sign language. When they realized how hard it was for them to try and understand what they were signing to each other, and thought about how hard it must have been for Lynn to try and understand them. In the end I’m glad that Louise and Tom decided to use sign language with Lynn because it made their lives so much easier and they were finally able to understand her and communicate with her without any problems.

Agency relationship Essay

1. INTRODUCTION Agency is a fiduciary relationship created by express or implied contract or by law, in which one party (the agent) may act on behalf of another party (the principal) and bind that other party by words and/or actions. The etymology of the word agent or agency says much. The words are derived from the Latin verb ago, agere (the respective noun agens, agentis). The word denotes one who acts, a doer, force or power that accomplishes things.1 Agency is the exception to the doctrine of privity under the law of contract. 2. LIABILITY OF A PRINCIPAL AGAINST THIRD PARTIES Lord Alverstone CJ in THE QUEEN V KANE2 defined an agent simply as ‘any person who happens to act on behalf of another’. A principal is one who authorizes another to act on his or her behalf as an agent. The general rule is that where an agent makes a contract on behalf of his principal, the contract is between the principal and the third party and prima facie at common law, the only person who can sue and be sued on the contract is the principal. The agent acquires no rights under the contract, nor does he incur any obligation. Having performed his task by bringing about a contract between his principal and a third party, the agent drops out of the picture subject to any outstanding matters between him and principal.3 The onus is on the person alleging that he entered into a contract with another person through an agent to prove that in fact the agent was acting as such. Agents of the state can never be personally liable for the state’s failure to perform a contractual obligation as stated in STICKROSE (PTY) LIMITED V THE PERMANENT SECRETARY MINISTRY OF FINANCE 4. In law, agents are recognized as having the power to affect the legal rights, liabilities and relationships of the principal. In CAVMONT MERCHANT BANK v AMAKA AGRICULTURAL HOLDINGS5, the Supreme Court held that where an agent in making the contract discloses both the interest and the names of the principal on whose behalf he purports to make a contract, the agent as a general rule is not liable to the other contracting party. Apart from having the power to affect the legal rights, liabilities and relationships of the principal, the agent may also affect the legal position of his principal in other ways. For instance, he may dispose of the principal’s property in  order to transfer ownership to a third party or he may acquire property on his principal’s behalf. Sometimes the actions of the agent may make the principal criminally liable as illustrated in the case of GARDENER v ACKEROYD 6.  The rights and liabilities of principal and agent against third parties may differ according to whether the agency is disclosed or undisclosed. The distinction between disclosed and disclosed agency is important as it affects the principal’s ability to ratify the agent’s actions. Furthermore, the agent’s liability to third parties may depend on whether the agency was disclosed or not. Agency is disclosed where the agent reveals that he is acting as an agent; if the agency is disclosed it is of no legal significance that the principal is not named. If an agent contracts with a third party without disclosing that he is acting as an agent the agency is undisclosed. 7 An undisclosed principal can intervene on the contracts of an agent within his actual authority. Where an agent makes a contract disclosing the agency, the normal rule is that a direct contractual relationship is created between the principal and the third party and either party can sue the other on the contract. It is important to note that only a disclosed principal can ratify an unauthorised contract. In KEIGHLEY MAXTED v DURANT8 a principal authorized an agent to buy wheat at a given price in the joint names of the principal and the agent. Having failed to purchase wheat at that higher price, the agent bought wheat in his own name at a higher price. The principal being satisfied with this act purportedly ratified the wheat purchase agreement at a higher price but failed to take delivery of the wheat. The seller then sued the principal arguing that the sale contract had been ratified. It was held that the action could not succeed because the agent’s act was unauthorized and since the principal’s identity had not been disclosed to the sellor, the principal could not ratify and consequently was not liable on the contract. Where the principal is disclosed, he and not the agent is liable on the contract and may sue and be sued. In GADD v HOUGHTON & CO.9 Houghton & Co. sold to the buyers Gadd, a quantity of oranges under a ‘sold note’ which stated, inter alia, that ‘we have this day sold to you on  account of James Morand & Co †¦.’ and signed ‘Houghton & Co.’ The seller having failed to deliver the oranges, the buyer sued Houghton & Co for damages for non-delivery. The action failed, since by the words of the sold note Houghton & Co had clearly indicated that they were not to be personally liable. They were merely brokers. Lord Mellish stated that â€Å"where you find a person in the body of the instrument treating himself as the seller or character, you can say that he intended to bind himself.† In SUI YIN KWAN & ANOTHER v EASTERN INSURANCE CO. LTD10 it was held that the doctrine of undisclosed principal applied. Where an agent acts within his actual authority the undisclosed principal may intervene and acquire the rights/liabilities of the agent. In this case, the agents acted within their actual authority and therefore, the relatives could recover from the insurance company. Lord Lloyd summarized the law as follows: (1) an undisclosed principal may sue and be sued on a contract made by an agent on his behalf, acting within the scope of his actual authority. (2) In entering into the contract, the agent must intend to act on the principal’s behalf. (3) The agent of an undisclosed principal may also sue and be sued on the contract. (4) Any defence which the third party may have against the agent is available against his principal. (5) The terms of the contract may, expressly or by implication, exclude the principal’s right to sue, and his liability to be sued. The contract itself, or the circumstances surrounding the contract, may show that the agent is the true and only principal. Sometimes the agent contracts with third parties after disclosing the fact, that he is an agent but without disclosing the name of his principal. In such cases, the principal is bound by the contracts made on his behalf. And thus, the principal is liable to third parties for his agent’s acts done on behalf of the principal. However, such acts must be within the scope of the agent’s authority, and the unnamed principal must be in existence at the time of contract. As a matter of fact, when the agent contracts after disclosing his representative character, the contract will be the contract of the principal. For all such acts, the agent is not personally liable. However, the agent is personally liable if he declines to disclose the identity of the principal when asked by the third parties. 11  When there is undisclosed agency, the contract is initially between agent and the third party and each may enforce the contract against the other. However, if the third party later discovers the principal’s existence, he may enforce the contract against either the agent or the principal. Provided that the agent acted within the scope of his actual authority, the principal can intervene and enforce the contract against the third party. 12 3. CIRCUMSTANCES WHEN AN AGENT MAY BE HELD PERSONALLY LIABLE If an agent continues to act after his authority has been terminated, he may incur personal liability for breach of implied warranty of authority. Sometimes an agent may suffer a potential risk when his authority is terminated automatically without his knowledge. In the case of YONGE v TOYNBEE13 where solicitors were acting in litigation for a client who, unknown to them, became mentally incapacitated so that the agency was considered to be terminated. However, they continued to litigate for the client and were held liable for their breach of warrant of authority and were ordered to pay the costs of the other litigant. There are three exceptional cases where the undisclosed principal cannot sue or be sued, by the third party. The first is where the contract between the agent and the third party expressly provides that the agent is the sole principal U.K MUTUAL STEAMSHIP ASSURANCE ASSOCIATION v NEVILL14. The second is where the terms of the contract are inconsistent with agency. In HUMBLE v HUNTER15, an agent signed a charter-party in his own name and described himself as â€Å"owner† of the ship. It was held that his undisclosed principal could not sue. The third case where an undisclosed principal cannot sue is where the identity of the principal is material to the third party. One such case is where the contract made between the agent and the third party is too personal to permit an undisclosed principal to intervene, for example, contracts for personal service. In the case of SAID v BUTT16, a theatre critic knew the management of a particular theatre would not sell him a ticket because of articles he had written. He obtained a ticket through an agent. It was held that the theatre could prevent the principal from  entering the theatre. McCardie J said that â€Å"the critic could not assert a right as an undisclosed principal since, as he knew, the theatre was not willing to contract with him†. Even where the undisclosed principal’s existence is discovered, the agent remains liable on the contract and the third party may choose to enforce the contract against either principal or the agent but not both. This is known as the right of election. A third party has an elective right to sue either the agent or the principal where the agent does not disclose the principal. In BOYTER V THOMSON17 the seller instructed agents to sell on his behalf a cabin cruiser under a brokerage and agency agreement. The buyer purchased the boat thinking it was owned by the agents and he was not told that the agents were acting as such nor the name of the owner nor that the owner was not selling in the course of a business although he was aware that the boat was being sold under a brokerage arrangement. The boat proved to be unseaworthy and was unfit for the purpose for which she was purchased. The buyer sued the seller for damages which were granted. The seller appealed to the House of Lords where goods were sold by an agent acting in the course of business for an undisclosed principal the buyer was entitled to sue not only the agent but also the principal. Once the third party elects to sue one party, his option to sue the other is extinguished. However, not any action by the third party suggesting action against one party in preference for another will be construed as the exercise of the right of election. In CURTIS v WILLIAMSON18, one Boulton appearing to act on his own behalf purchased some gunpowder from the plaintiff. Later, the plaintiff discovered that Boutlton was acting on behalf of an undisclosed principal, the defendant mine owners. Boulton then filed a petition of liquidation and the plaintiff filed an affidavit in those proceedings in an attempt to recover the debt owed for the gunpowder. However, the plaintiff changed their mind and sued the defendant principal. It was held that once an undisclosed principal is discovered the third party may elect to sue that principal; and secondly, that the filing of the affidavit against the agent did not prevent the action against the principal. The third party will not be bound by an election unless he has unequivocally indicated his intention to hold one party liable and release the other. The doctrine of the undisclosed  principal exists for purposes of commercial convenience, it is important to maintain protections for the third party. In the situation where the agent has failed to pass the payment to the third party, either the principal or the third party will lose and it seems fairest to place the loss on the principal.19 4. HOW AGENCY MAY BE DETERMINED As the relationship between the agent and his principal is based on consent, actual authority is of paramount importance. An agent is only entitled to be paid if he acts within his actual authority. If he acts outside his authority he may be liable to his principal. The relationship between the principal and a third party depends on the agent’s power to bind his principal. However, what is of concern to the third party is the agent’s apparent authority as this is what he relies on in the ordinary course of events. There are several types of authority. These are: a) Express Authority – the agreement between a principal and agent may be express or implied. Express agreement may be made orally, in writing or by deed. In general, if an agent is appointed to execute a deed his appointment is by deed called a power of attorney. b) Implied Authority arises where, although a particular action is not sanctioned by express agreement between the principal and the agent, the principal is nevertheless taken to have impliedly consented to the action or transaction in question. In GARNAC GRAIN CO. v H.M.F. FAURE AND FAIRCLOUGH20 the House of Lords stated that â€Å"the relationship of principal and agent can only be established by the consent of the principal and agent. They will be taken to have consented if they have agreed to what amounts at law as a relationship even if they do not recognize it themselves and even if they have professed to disclaim it. An agent who has express authority to carry out a particular task may also have additional authority to do certain acts incidental to his authorized task For instance, an agent authorized to sell the principal’s property has implied incidental authority to sign a contract of sale.† c) Apparent Authority – a person may be bound by the acts of another done on his behalf without his consent or even in breach of an express prohibition if his words or conduct create the impression that he has authorized the other person to act on his behalf. This is described at law as â€Å"apparent agency or  authority† or â€Å"ostensible agency or authority†. The distinction between actual and apparent authority was explained by Diplock L.J. in FREEMAN & LOCKYER V. BUCKHURST PARK PROPERTIES21. â€Å"Apparent† or â€Å"ostensible† authority, is a legal relationship between the principal and the contractor created by a representation, made by the principal to the contractor, intended to be and in fact acted on by the contractor, that the agent has authority to enter on behalf of the principal into a contract of a kind within the scope of the â€Å"apparent† authority, so as to render the principal liable to perform any obligations imposed on him by such contract. To the relationship so created the agent is a stranger. He need not be (although he generally is) aware of the existence of the representation. The representation, when acted on by the contractor by entering into a contract with the agent, operates as an estoppel, preventing the principal from asserting that he is not bound by the contract. It is irrelevant whether the agent had actual authority to enter into the contract. d) Agents of Necessity – A person who acts in an emergency, for instance, to preserve the property or interest of another may be treated as an agent of necessity. His actions will be deemed to have been authorized even if no actual authority is given. Like apparent authority, an agency of necessity can arise even in the absence of consent from the principal. Agency of necessity only arises in extreme circumstances where there is actual and definite commercial necessity for the agent’s actions. The following must be satisfied for an agency of necessity to exist: (i) There must be an emergency – something unforeseen. (ii) It must be practically impossible to get instructions for the principal. (iii) The agent must act bona fide in the interest of the principal rather than to advance his own interests. He must not take advantage of the principal. (iv) The agent must act reasonably in the circumstances. e) Agency arising out of Co-habitation – It is argued that a wife has authority to pledge the credit of her husband for necessities (or vice versa). However, others argue that social conditions now make it old fashioned to suggest that actual or apparent authority should not arise  between husband and wife. The law recognizes the following as agents even though they do not bear the title of agent22: (a) Company Directors and other company officials – being an artificial person, a company has to act through human agents. Then authority to act as company agents is vested in the board of directors. This authority may be delegated to one or more executive directors by the articles of the company to allow him to manage the day-to-day operations of the company. (b) Partnerships – as a partnership has no separate legal identity from its members, every partner in a firm is an agent of the firm as well as all other partners for the purpose of the business of the firm. Thus, a partner who performs an act for the purpose of carrying out the business of the firm, binds the firm as well as the other partners. (c) Employees – may be servants working under a contract of service or an independent contractor working under a contract for services. An employee e.g. a shop assistant is the agent of the shop owner for the purposes of making a contract of sale for the owner. He has the authority to make statements about goods that are binding on the shop owner, his employer. (d) Professionals – acting on behalf of clients may be the agents of those clients. E.g. a lawyer conducting litigation is his client’s agent and may have authority to settle the case and that settlement will bind the client. Thus the lawyer, not the client, normally signs a consent judgment. Similarly, an accountant’s agreement or statement to ZRA will bind his client in accordance with agency principles. The relationship between principal and agent depends on consent. If withdrawn, the agency will automatically end, as well as the agent’s actual authority to bind the principal. An agency relationship may be terminated in the following ways: (a) By mutual consent between the agent and the principal. (b) By either party unilaterally withdrawing consent. (c) An agent may have been appointed for a fixed period of time or for a specific task or set of tasks. Once the time elapses or the task(s) is/are completed the agency will terminate. (d) By operation of law e.g. if the  performance of the agency relationship becomes illegal (e.g. one party becomes the citizen of an alien enemy) or impossible (where it will be ended by the agency contract being frustrated). Death of either party will also terminate the agency and any contract made between them. If an agent becomes insane, the relationship is automatically terminated. The bankruptcy of either the agent or the principal will also end the agency.23 The Effect of Termination vis a vis Third Parties The agent may continue to have apparent authority even if actual authority has been terminated. If the principal’s conduct is such as to suggest to a third party that the agent continues to have authority. Until the principal brings the termination of the agent’s authority to the notice of a third party, the agent may continue to have apparent authority on the strength of the principal’s representation. DREW v NUNN24 the principal became insane but his wife, who was his agent, continued to act in his name. When he recovered from his insanity he tried to disclaim liability for acts done by his wife during his insanity/incapacity. Held: The agent i.e. his wife, had apparent authority and therefore he was bound. However, where an agent’s actual authority is terminated by the principal’s death or bankruptcy the agent will automatically cease to have apparent authority.

Social Contexts Essays - Art History, Realism, Food Security

Social Contexts Essays - Art History, Realism, Food Security Social Contexts Art in Canada FFAR 250 Social Contexts presented to Mark Mullin on December 3, 1999 written by Marguerite Gravelle 4320662 1. When analysing an artwork what is to be gained from considering the social context in which it was created? Are there possible drawbacks to this methodology? Provide clear examples to substantiate your argument. When analysing artwork, in any form, there are often times social contexts in which can be interpreted. Not always does the history behind the painting need to be revealed to fully understand the concept of the artwork, yet it is helpful in determining if the artwork is truthful in its representation. Although in analysing artwork it is likely that there are drawbacks to considering the social context. To illustrate this point, I'm going to use the visual arts as my medium of choice. Understanding the social context can be an important tool. An advantage of knowing the history of the painting or sculpture can really enrich our knowledge, being in the 20th (soon to be 21st) century, about some of the social periods from previous times. It can demonstrate how traditions were carried out, how they had an impact on the different social classes. It's a visual teaching aid of a sort. Even in the time period of which the artwork was created can be used as a tool to show how the life was in different parts of the world. It was also used as a hammer in the realist movement to show the upper classes that life for the poor was horrible. The visual arts is the only medium in which the pictorial image creates a universal language in which anyone, regardless of nationality or social class can interpret. The text which is created by this language often creates a context which is left open to interpretation. Contexts are created by the artist, critics, judges, the public, essentially, any one who views the work and forms an opinion relating to it. The contexts stem from subject or content of an artwork, and are usually facts regarding the content. Yet, the contexts almost always have backgrounds themselves, therefore making the original contexts, texts. This will be more clearly illustrated later. The chain is seeming to be a never ending process. There are always more conditions to the previous ones. All context, therefore, is in itself, textual. This concept of all context in itself textual is a post-structuralist strategy. A man named Derrida is a man who has developed this idea that the post-structuralist concept of every statement made, can be interpreted in infinite ways, with each interpretation triggering a range of subjective associations. Every statement has an association, therefore it's a sort of domino effect. He also says that no matter how precise a work strives to be, the absolute meaning can never be found due to this never ending sequence. To better illustrate this concept, I have chosen a painting from the mid-nineteenth century. It was painted by a french artist in 1854 named Jules Breton. It is called The Gleaners(figure 1). The gleaners were impoverished women who picked the left-over wheat from the farmers' fields after they had been ploughed to bake bread for their families. In this painting there are numerous women who's arms are brimming with wheat. The women are beautiful, healthy looking. The children even seem happy running around playing next to their mothers. There are many contexts which can be extracted from The Gleaners. A major influence would be the revolution in France in 1848. Perhaps the gleaning laws enforced in 1851, even the physical health of the gleaners. For arguments sake, let's take the physical health of the gleaners to show how a statement can trigger other associations. The physical health of the gleaners in the 1850's could be researched in the reports from the army conscripts. The conscripts were usually poor men who wanted a secure and stable job. These reports showed that most of the men were of poor health and diseased. These reports can be associated with who was writing the reports, officers? The associations never cease. We can never fully determine what the health was of the gleaners because every context we take will lead to another context. The key point in this image

Schumann Mr. and Mrs Romanticism Essays

Schumann Mr. and Mrs Romanticism Essays Schumann Mr. and Mrs Romanticism Essay Schumann Mr. and Mrs Romanticism Essay Schumann: Mr. Mrs. RomanticismJessi AbbegHUM 2510 Music AppreciationSeptember 11, 2013Professor Wendy GilletteIntroduction As philosophers of the Romantic Movement searched for a new understanding, they turned from the analytical, attempted more subjectivity than objectivity, and began to embrace rather than to examine. The Romantic’s began to value man based on their passion and emotions, to strive for creativity and expression, and to cultivate intuition and imagination. Consequently, this caused a shift away from order to chaos, from answers to questions, from predictability and reasons to uncertainty. Accordingly, uncertainty became the only assurance, the convention of Romanticism, and the very essence of the Romantic Era. The resulting philosophy eventually led to an artistic resurgence through which music gained importance as a powerful means of expression, and a significant standing within the culture. . Robert SchumannMore than one esteemed musical mind has called R obert Schumann the spirit of the romantic age - an age that was nothing if not spirited. Editor-critic and composer Robert Schumann (1810-1856), personifies views of Romanticism in theory and practice: his life speaks of great imagination and pain, his compositional style of invention and ambiguity. A composer throughout the early- to mid-nineteenth century, he is probably best known for his songs and piano works. Before injuring his finger most likely with a chiroplast (an instrument that guides the hands while playing; highly controversial), Schumann was an avid piano player, if not a proper concert pianist and virtuoso (Kamien). Nevertheless, due to this ailing finger, Schumann had to eventually find other means to support his life. Thankfully for us, he eventually turned to composition, and furthermore, to piano composition.During his lifetime, he composed four symphonies and numerous piano works all of which were not always well received immediately, because

Sex and the City TV Show Quotations

Sex and the City TV Show Quotations A perfect play on words, Sex and the City quotes are full of witticisms and unabashed humor.  Here is a refreshing collection of Sex and the City quotes for good coffee-time reading.   Great Quotes From Sex and the City Charlotte: I just know no matter how good I feel about myself, if I see Christy Turlington, I just wanna give up.Miranda: Well I just want to tie her down and force feed her lard, but thats the difference between you and me.Carrie: [to Big] Were so over we need a new word for over.Miranda: Im sorry, if a man is over thirty and single, theres something wrong with him. Its Darwinian. Theyre being weeded out or propagating the species.Detective: You Irish?Miranda: No, why?Detective: Coz you have beautiful red hair.Miranda: Well I guess anybody can be Irish with the right colorist.Carrie: There are 1.3 million single men in New York, 1.8 million single women, and of these more than 3 million people, about 12 think theyre having enough sex.Carrie: I like my money where I can see it - hanging in my closet.Miranda: Whatever happened to aging gracefully?Carrie: It got old.Carrie: When it comes to relationships, maybe we’re all in glass houses, and shouldn’t throw stones. Becaus e you can never really know. Some people are settling down, some are settling and some people refuse to settle for anything less than butterflies. Samanthas terrified to get an AIDS test...Samantha: What if I have it?Carrie: You dont have it.Samantha: Sometimes it takes me a really long time to get over a cold.Carrie: Thats not AIDS, thats central air conditioning.Samantha: Im a try-sexual. Ill try anything once.Miranda: Theyre starting to die on us.Charlotte: Oh my god.Samantha: Well at least you werent stood up.Miranda: 35 and theyre dying. We should just give up now.Carrie: Well, on the bright side, this could explain why they dont call back.Samantha: Hmm.Charlotte: How did he... ?Miranda: Heart attack.Samantha: Oh.Miranda: At the gym.Carrie: See, this is why I dont work out.Miranda: My marriage is going through a rough spot. I dont have time to wax!Samantha: [Upon seeing a firefighter stripper] Hello, 911. Im on fire!Carrie: Maybe some women arent meant to be tamed. Maybe they just need to run free until they find someone just as wild to run with.Mr. Big: Nice dress.Carrie: Meaning?Mr. Big: Nice dress.Carrie: [after hearing Big is moving to Napa, California] If your tired of New York you take a napa, you dont move to Napa! Charlotte: [On seeing the tacky floral arrangement at Mirandas mothers funeral] They were supposed to say Im sorry, I love you not Youre dead, lets disco!.Samantha: [to the girls] I think I have monogamy. I caught it from you.Carrie: Yes, its airborne.Charlotte: I was a teen model when the Ralph Lauren store opened in New Haven.Miranda: Okay, it was amazing that I could keep my lunch down just now.Miranda: Wow! A guy who doesnt want to get married! Film at eleven!Charlotte: So, which church does his mother go to?Carrie: Park Avenue Presbyterian.Charlotte: Good church! Its one of the best on the east side!Carrie: What, are you rating churches? Is there a Zagat guide for that?Miranda: Four stars. Great bread; disappointing wine selection. Carrie:  Now Ive laid down a gauntlet. He either has to say I love you back or I guess Im going to have to break up with him.Charlotte:  Well, how long are you going to give him?Carrie:  Well, I didnt put an expiration date on the sentiment, but I figure its got the shelf life of a dairy product. Its going to start to curdle in about a week.Duncan:  Im just one of those weird male aberrations who  prefers  to be married. I like stability, I like routine. I like knowing  theres  people waiting for me at home. I guess that makes me sound pretty dull.Miranda:  Are you kidding? Youre the heterosexual holy grail.Carrie:  So what type of movies do you compose for?Patrick:  Really bad ones. You know, the I Screamed When I Knew What You Did Last Summer on Elm Street type.Samantha:  You know, women dressing like men is very popular right now.Carrie:  And here I thought it was Pokemon.Steve:  Oh come on, I want a baby. It would be fun.Miranda:  Its not like owning a foosball table, Steve.Aidan:  Dont take this the wrong way but this place could use a little work.Carrie:  I know, but I cant afford it.Aidan:  Youve got eight thousand bucks worth of shoes over there.Carrie:  I needed those! Miranda:  (looking at a bride magazine)  Ooh! Cute purse!Charlotte:  No purses! Theres no time for purses! This is gown-specific!Miranda:  Whats your theme again? A Nazi wedding?Carrie:  Id like to think that people have more than one soulmate.Samantha:  I agree! Ive had hundreds.Carrie:  Yeah! And you know what, if you miss one, along comes another one. Like cabs.Charlotte:  I promise I wont become one of those mothers who can only talk about diaper genies.Carrie:  Good.Samantha:  What the hell is a diaper genie?Carrie:  I dont know... someone you hire to change a kids diaper?Samantha:  These fast food apple pies are surprisingly delicious!Carrie:  I know! Why would anybody go to the trouble of making one when you can buy one that is so perfect and individually sized?A performance artist is starving herself and refusing to speak while on public display.Aleksandr:  You dont think its significant?Carrie:  Oh please! There are depressed women all over New York doing the exact same thing as her and not calling it art. I mean, if you put a phone up on that platform, its just a typical Friday night waiting for some guy to call. Samantha:  (on not getting hired because shes a woman)  What does he think Im gonna do? Get my period and ruin his empire?!FBI Agent, to Samantha:  Maam, can you undo your cuffs so we can use ours?Miranda:  He has to get baptized and wear a dress.Carrie:  Babys first drag show!Carrie:  Ooh! I forgot about the washer and dryer! Ive been dreaming about that my whole New York life!Samantha:  Whos the farmer with the dells?Carrie:  Young MacDonald?Samantha:  Oooh! E-I-E-I-O!Guy:  This floors  non smoking!Carrie:  I have an addiction, sir!Carrie:  It was a typical downtown male mix. Ten percent Wall Street, ten percent real estate, and ten percent Samantha had already slept with.Charlotte:  I proposed myself!Carrie:  What?Charlotte:  Yes. I suggested he have a tomato salad, then I suggested we get married.Carrie:  Wait. What exactly did he say?Charlotte:  Alrighty!Carrie:  Alrighty?  He said  alrighty? Now Im thinking the upsetting thing isnt that you proposed, its that you proposed to a guy that says alrighty.Charlotte:  Oh, Carrie, stop!Carrie:  Alrighty. Charlotte:  ...you shouldnt be talking like that at all, Samantha, its rude and politically incorrect.Carrie:  Sweetie, a reminder: Samantha is rude and politically incorrect.Miranda:  Shes an equal opportunity offender.Miranda:  You double-booked?Carrie:  How do you conceive pulling this one off?Charlotte:  Early dinner with bachelor number one, late supper with bachelor number two.Samantha:  My god, youre turning into a man!Carrie voiceover:  Apparently Charlotte had done more than just break a pattern. She had actually changed genders.Charlotte:  I just dont know how Im going to eat two dinners in a row.Carrie voiceover:  And just like that, she was a woman again.Big:  I never really thought about it.Carrie:  Oh come on. Everybody wonders what happens after you die.Big:  Im too busy wondering whos dinging my car in the garage.Carrie:  If you keep talking like that Im going to have to charge you by the minute.Anthony on his cell:  Charlottes wedding dr ess stylist Sorry, thought it was my Mother. FIFTEEN phone calls to make sure I get her the cheapest possible sheets from Bed, Bath and Friggin Beyond! Carrie:  And then I realized something, twenty-something girls are just fabulous, until you see one with the man who broke your heart.Charlotte:  Trey, you have a boner... I cant discuss my notes if you have a boner.

Why books are undergoing disruption Research Paper

Why books are undergoing disruption - Research Paper Example Talking in a detailed manner, the development of the internet powered communication technology along with the factor of rapid rise and faster acceptance of various kinds of technological gadgets has resulted in the process of a massive global technological revolution. As a result of this revolution, the world has been automatically transformed into a single well connected global entity. It needs special highlighting of the fact that the technological revolution that has affected both the developed as well as the developing markets has brought a tremendous change in the nature and behaviour of the masses around the world. The masses of the present day increasingly prefer to live a dual life. This dual life promotes physical presence in the real world as well as virtual presence in the internet connected world. In order to stay connected to their virtual selves in the virtual world, the masses prefer to acquire various smart technology devices like Smartphones, I-pads, tablets. These t echnological devices besides helping the masses to stay connected to the virtual world, also comprises of a number of technology powered applications. These applications automatically results in bringing a change in the behaviour of the masses. In this tech savvy era, it has become a common trend of the masses to use the technological gadgets as much as possible for the accomplishment of daily work as well as even gaining access to knowledge and related resources. Thus this has automatically given the base for the rise in demand for books in the electronic medium. The Innovation factor in EBooks The rise in demand for e-books automatically represents that the books in the physical medium is getting obsolete in nature. In order to understand the nature of change that is happening in the book arena, the focus has to be given on innovation. The nature of innovation can be incremental as well as disruptive. Incremental innovation represents the process of adding and increasing the value of the existing products in a step by step manner (Shavinina, 2003, p. 120). On the other hand, disruptive innovation means a sudden surge in value as compared to the already existing model of product. This sudden and massive increase in value might result in the process of making the previously existing product look outdated in nature. However, a disruptive innovation takes a longer time to gain stability as compared to the incremental innovation (Kelley, 2010, p. 32). A very important feature of disruptive innovation is that it ends up creating a new market for a new segment of customers (Bjarnason, 2013). In case of eBooks, a very similar kind of pattern can be identified. Before eBooks emerged into existence, there was no market for this kind of a product and the customers preferred to read and gather information from the physical book form. However, the evolution of eBooks resulted in the development of a new market where customers preferred to take the enjoyment of book readi ng from the technology enabled media and gadgets. a. In this particular case, it needs to be highlighted that the company that is dealing with eBooks has a first mover advantage. Now, in case of a company, that have a first mover advantage with eBooks, it simply represents that the company is trying to promote and stabilize the market as well as create a demand for eBooks, a product which has been developed on the lines of disruptive innovation. However, it is important to mention that the product might fail despite having a first mover adv

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What Happens to Kids When Parents Do Not Pay Attention to Them because They Are Busy Working - Essay Example Children are totally dependent on adults at the time of birth, and to a great extent till the time they are equipped with the tools to be able to fend for themselves. Besides the basic physical needs of a child like food, clothing, medical care, education and a safe environment in which to grow; other needs that are of great importance to a child’s well being, and those that can impact the child’s future, are emotional needs; that if neglected, can scar a child for life, and cause untold damage to the child as well as to the society in which s/he lives. The problems of neglect among today’s kids are increasing. Till the first part of the twentieth century, these problems were not so evident. The support of extended families and the role of the mother who was a homemaker, ensured that enough time was given to kids although families were larger then, than they are today. As more and more women began to work and set up nuclear families the problem of children's need s being neglected has arisen, and of late has assumed gargantuan proportions. Today parents’ neglect of their children stems not just from lack of time or resources, but often is caused by parents being more self centered and putting their own need for having a good time before the needs of their children. Sometimes it is also caused because parents themselves have been victims of neglect and /or victims of drug abuse. It is shocking that these problems should arise at a time when family planning methods are easily available and parents have the choice of planning their family. Raising a child is a tremendous responsibility and the best parents have sometimes been stumped by the demands and pressures that a child is capable of putting on them. There is no question of quality time. Child raising is a job without hours and one that can try the patience of a saint. Yet, according to many parents who have successfully raised families with all the attendant problems, it is a treme ndously satisfying and joyful experience. Those parents who can balance work and home life find that parenting is less stressful. One has to re-evaluate priorities and make some choices and hard decisions when one plans a family. A parent’s love for the child is the motivating factor that goads parents to make many adjustments in their lifestyle for their children. The bond that develops between loving, caring parents and their children makes children want to please their parents. The development of this bond of love between parents and their children is an important factor for the healthy physical, mental and emotional development of children, that can have long term consequences on the kind of human beings that children grow up to be. Babies need a lot of time because they are so helpless and need parents to fulfil every need. During the first few months after childbirth, the mother too is going through a lot of emotional stress and needs the support of her husband and othe r close family members. As the child begins to grow, s/he is learning at a fast pace and the need to feel loved, protected and secure is very great. At this point the toddler needs the reassurance of being loved and valued. As s/he conquers new milestones, the pride of parents in his/her achievement is the highlight of the toddler’s day and s/he strives to repeat the newly learned skill. In the growing years, children often have to be reprimanded for bad behavior or mistakes that are an inevitable part of growing up. At such times parents must ensure that the child’s mistake has been explained and understood. If a child does not understand why s/he is punished the same mistakes

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Property law - Essay Example Furthermore, it is Debra who has been making payments on the mortgage for five years and she was also the guarantor for Fred in the initial few years. As a result, she is the one who has a considerable financial investment in the house. The basic principle that applies in the case of voluntary dealings is the presumption that a person making a transfer intends that the transferee remains a nominee only, while the person making the transfer is to retain a beneficial interest in the property2. This applies in the case of Fred, who originally had the title to the property, but later transferred it to Debra. It may be possible to apply proprietary estoppel on the basis of representation3, i.e, despite Debra owning title to the property, Fred is to have rights in respect of the property. As a result of such rights which Fred may have in the property because he has been living in the council house and the property was also in his name initially, his interests in the property may pass on a beneficial interest to Stan.4 But in this instance, it must be noted that Fred has not left a will, therefore the question of beneficial interest in the property passing through the will5 does not apply. In arriving at a determination of whether or not equity will apply, Lord Scarman has stated that the conduct and relationship of the parties must answer three questions: â€Å"First, is there an equity established? Secondly, what is the extent of the equity, if one is established? And, thirdly, what is the relief appropriate to satisfy the equity?"6 Firstly, in establishing whether Fred was the substantial owner in equity, the question that arises is whether Debra allowed or encouraged Fred to assume that he had rights in the property, rather than a mere hope for such rights, which is not sufficient7. In this case, it was Fred who was the continuous resident of the council house and Debra was the one who moved back in with him. Furthermore,

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Political science - Essay Example al political systems, supranationalism, peace studies, conflict analysis, strategic studies, public administration, political psychology, socialization studies, legislative processes, public law, and more. The issue of how globalization is impacting citizenship is one of great significance within the field of political science, and it is as well one which is highly relevant to the world today. In order to be able to understand about globalization and how it is affecting citizenship today, not only must each separate issue be discussed, but as well any and all other key issues must be addressed and thoroughly examined. By doing this, we will be able to gain a more informed and knowledgeable understanding on the subject matter at hand, and as well we will be able to attain the information which will answer the question of how globalization is affecting citizenship. This is what will be dissertated in the following. Globalization is a term which refers to a process that involves the increasing of global connectivity and the integration between organizations, and it is really an umbrella term which covers a variety of different ideals. Recent emerging literature and studies on the quality of democracy have suggested the fact that economic globalization greatly affects the quality of citizenship, and there are three particular of facets of globalization which must then be discussed here, as well as two facets of social citizenship. The three globalization facets are trade level, trade liberalization and debt ratio; the three social citizenship facets are social spending and employment quality. The problems that are considered to exist between globalization and citizenship are not considered as being new, as in fact there have been many steps that have been taken in the past, particularly over more recent years, in order to try and create solutions for these specific problems. For instance, in December, 1996, UNRISD (United Nations Research Institute for Social

Alcoholic Drinking Age Research Paper Example | Topics and Well Written Essays - 2000 words

Alcoholic Drinking Age - Research Paper Example Arguments would be presented in the favor of this proposition and will try to explore and counter the arguments presented against this proposition as well. After the repeal of prohibition in the â€Å"year 1933, many states in the United States set the minimum drinking age limit at 21 years and some states set the limit at 18 years for the purchase of beer† (Liddle & Rowe, 54-55). However, during the late 1960s and 1970s, due to drafting of young individuals to the war and the growing trend of liberalism, almost all states decreased the minimum drinking age to 18 years. However, the results on paper were not favourable. In the year 1982, President Ronald Regan decided to make a committee in order to provide solutions for these increasing drinking related incidents. The committee strongly proposed to increase the minimum drinking age from 18 to 21 years. The federal government passed a legislation forcing the states to do the same and by the end of the year 1948, 23 states had increase the minimum drinking age to 21. On July 17 of that year, the federal government passed a legislation, which allowed the federation to withhold fun ds of the 27 states that were not ready to increase the minimum drinking age limit in an attempt to force them to do so. ... fined 52 US dollars along with eight hours of community service and six hours of alcohol awareness classes since the authorities found her holding a glass of beer (United States Office of National Drug Control Policy, 24-26). This debate then received widespread media attention when former student council president from more than 100 reputable universities of the United States started a campaign to force the government to repeal the minimum drinking age from 21 to 18. They believe that the minimum drinking age limit of 21 years has been there for over a couple of decades and it has no good for the country. Teenagers continue to drink during their college and university lives, worse they drink in unsupervised conditions where in the absence of any regulator, adult or guardian, they end up crossing all possible limits and evoke long lasting health problems for themselves (Hanson, Venturelli, & Fleckenstein, 352-354). Discussion United States, Indonesia, Kazakhstan, India, Sri Lanka, Ta jikistan, United Arab Emirates, Palau, Solomon Islands, American Samoa, Federated States of Micronesia, Northern Marina Islands, and Fiji are the only countries, which have raised their dinking limit to 21 years instead of 18 years. However, all other countries in the world the minimum drinking age is of eighteen years. Eighteen years is considered as the â€Å"age of majority† in law as well. In addition, 18 years is seen as the symbol of maturity at which age the person gets the chance to enter into legal contracts and the contract of marriage, join the armed forces, and vote in elections and other legal rights and duties (Liddle & Rowe, 54-55). One can get married when he or she reaches the age of 18, however, he or she would not be allowed to drink on their own wedding if their age is

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Political science - Essay Example al political systems, supranationalism, peace studies, conflict analysis, strategic studies, public administration, political psychology, socialization studies, legislative processes, public law, and more. The issue of how globalization is impacting citizenship is one of great significance within the field of political science, and it is as well one which is highly relevant to the world today. In order to be able to understand about globalization and how it is affecting citizenship today, not only must each separate issue be discussed, but as well any and all other key issues must be addressed and thoroughly examined. By doing this, we will be able to gain a more informed and knowledgeable understanding on the subject matter at hand, and as well we will be able to attain the information which will answer the question of how globalization is affecting citizenship. This is what will be dissertated in the following. Globalization is a term which refers to a process that involves the increasing of global connectivity and the integration between organizations, and it is really an umbrella term which covers a variety of different ideals. Recent emerging literature and studies on the quality of democracy have suggested the fact that economic globalization greatly affects the quality of citizenship, and there are three particular of facets of globalization which must then be discussed here, as well as two facets of social citizenship. The three globalization facets are trade level, trade liberalization and debt ratio; the three social citizenship facets are social spending and employment quality. The problems that are considered to exist between globalization and citizenship are not considered as being new, as in fact there have been many steps that have been taken in the past, particularly over more recent years, in order to try and create solutions for these specific problems. For instance, in December, 1996, UNRISD (United Nations Research Institute for Social

Japan Earthquakes' Effect on Japan's Environemnt Research Paper

Japan Earthquakes' Effect on Japan's Environemnt - Research Paper Example In 2011, Japan recorded the strongest earthquake in the recent past, which later triggered a devastating tsunami along the northern pacific coast. This earthquake, named the Great East Japan earthquake, caused massive losses in Japan. The 9.0 earthquake caused a 124 foot tsunami wave, deaths of close to 20’000 people, and massive destruction of homes. Apart from these losses, the earthquake caused the nuclear accident that occurred in Fukushima Prefecture (LÃ ¼sted 4). The fact that Japan is an earthquake prone country makes it prepare for such happenings. In 2011 earthquake, tsunami early warning signs enabled Japan to take the necessary precautionary measures that helped in saving hundreds of thousands of lives. Unfortunately, the 2011 earthquake struck with massive waves that were of bigger magnitude than it was previously predicted. This was the reason why many people lost their lives, massive property destruction, and severe damage on the environment. The massive losses of lives that are evident in different earthquakes that have struck Japan are mainly due to subsequent effects that follow an earthquake. Majority of these effects are environmental in nature, and their impacts may last for a prolonged period of time (LÃ ¼sted 11).usted 11). What is an earthquake? An earthquake refers to a sudden movement of the earth due to an abrupt release of energy that has piled up over a prolonged period. Numerous studies support that a majority of earth quakes occur along boundaries where plates making the earth’s outer layer meet. Scientists use the knowledge of locations where earthquakes take place and the nature of ruptures they produce to describe the plates boundaries. It is worth noting that a majority of destructive earthquakes are as a result of dislocation of the earth’s crust. In such situations, the crust exacts its effects by bending and then breaks and snaps to a new position when the prevailing stress exceeds the pressure exerted by rocks (Alexander 47). The earth has three types of plate boundaries. The first boundaries are the spreading zones. In these zones, molten rock material rises up; this leads to the separation of two plates and addition of material along their edges. Spreading zones are most common in oceans. The second types of boundaries are the transform faults, which occur where plates move past each other. Earthquakes that occur along these plates happen at shallow depths, leading to visi ble straight linear patterns. The third types of plates are the subduction zones, which occur in earth’s regions where one plate subducts another plate. This phenomenon pushes the subducted plate downwards into the mantle causing it to melt. Subduction zones form shallow or deep earthquakes, deep ocean trenches, and mountain ranges that have volcanic activities (Alexander 55). Geologists have evidence that supports the idea that earthquakes occur frequently along faults. These regions of the earth show areas of weakness along the earth’s crust. Once an earthquake has occurred along a fault zone, it is unlikely that all stress is relieved from the earth crust. This situation creates a chance for another earthquake to occur in the future. In some cases, earthquakes are likely to strike before, during or after a volcanic activity. In this case, earthquakes are not linked to the occurrence of the volcanic eruptions, but the force associated with the volcanic eruption cause s the earthquakes to happen (Oxlade 35). Seismographs are the

Act of Concern Essay Example for Free

Act of Concern Essay The average Filipino generates 0.3 and 0.5 kilograms of garbage daily in rural and urban areas, respectively. A recent Asian Development Bank (ADB) 2004 study showed that 6,700 MT of waste is generated daily in Metro Manila. Annual waste generation is expected to grow 40% by 2010 These garbage come in many forms: the styrofoams used by a fast food chain, a broken pair of slippers and wrappers of various snacks are just some examples. For the past decades, issues regarding disposal of these large amount of waste have been a primary concern. Landfill sites continuously blow as more garbage is generated. However, economists would say resources are scarce and limited especially in land. Thus in 2002, the Supreme Court decided to pass Republic Act 8749 or the Clean Air Act of 1999 making the Philippines the first country to ban burning or incineration of all wastes. Incineration is a waste treatment process which uses combustion. Waste materials are converted into ash, flue gas and heat. Incineration does not totally replace landfill sites but rather significantly reduces the volumes of wastes necessary for disposal1 (Wikipedia). But beneath this supposedly positive output lies the harmful effects of incineration to the environment. Environmentalists claim that burning waste materials result to numerous negative environmental, social and health effects. Some of these harms are: †¢ Poison to the environment, human body, and food supply with toxic chemicals. The release of gases like dioxin during the burning process is harmful to every human life. †¢ Production of toxic byproducts †¢ Undermining of waste prevention and recycling †¢ Contribution to global climate change †¢ Generation of waste energy and destruction of vast quantities of resources †¢ Violation of the principles of environmental justice When the ban of combustion was lifted, there went opposition from various groups that were directly affected. These groups were businessmen, firms and rich individuals involved in the business and industrialized sector, for the reason that they find incineration as the easiest and cheapest method of waste reduction. Such a self-centered way of thinking cannot be changed by any reasoning. And â€Å"nature’s revenge† has its means to get even. At the outset, www.hubpages.com reported that 377 people died, 32 still missing and Php 10 billion or over $200 million worth of damage to infrastructure, crops and properties were lost when typhoon â€Å"Ondoy† devastated the whole country last September 26, 2009. Even some parts of the Metro Manila had been temporarily removed in the map. It was noted as one of the most alarming catastrophes in the country’s history. Not only houses, buildings and establishments were destroyed but also families who have lost their beloved relatives. Indeed, the incident had left people nothing but sorrow. Other than this, the Payatas tragedy is also an alarming result of this garbage problem in the country. These incidences would not probably happen if the government has not failed to implement an effective and efficient waste reduction program. So, even though the government has its loop holes or shortcomings in terms of the full implementation process, everyone should be concerned in taking care of the environment. We must all be responsible for our actions. And to quote from one professor â€Å"even the smallest thing we do can make or break our resources.† In the end, if the state will not follow the rules and regulations those will be futile ones and should be abandoned.

Treatments for Metronidazole-Resistant Giardiasis A Review

Treatments for Metronidazole-Resistant Giardiasis A Review Nicole Wagner Abstract Giardiasis is a protozoal infection and a health issue in many parts of the world for both humans and animals. Giardia spp. Are responsible for diarrheal diseases, and current treatments are not consistently effective due to the development of drug resistance. The common drugs used to treat the parasite often have undesirable side effects. New drugs, drugs previously used for other conditions, and natural remedies are all being investigated for use in treating giardiasis and reducing Giardia numbers. The mode-of-action and potency of these alternative treatments give insight into new therapies, although more research is needed. Introduction Protozoal Giardia spp. Occur in two forms, a motile, flagellated trophozoite, and a resistant cyst. The motile trophozoite adheres to the intestinal wall of its host, while the cyst form is passed in the hosts feces then re-ingested in another host (Hendrix and Robinson 2012). It is now suspected that Giardia is species specific and the human forms are included in the Giardia lamblia assemblage and include Giardia intestinalis and Giardia duodenalis (Hendrix and Robinson 2012). Giardiasis is caused by a protozoal parasite that is responsible for health issues worldwide in humans and animals. In humans, the parasite is responsible for approximately 184 million cases of giardiasis each year (Hart et al. 2015). In animals, it has been found that in North America some herds of dairy calves have the parasite in 100% of the animals, and in Australia, the most common enteric parasite of dogs is a species of Giardia (Thompson. 2000). Signs and symptoms of giardiasis include chronic and acute diarrhea and vomiting (Hart et al. 2015). These significant intestinal diseases can decrease appetite, cause malabsorption, malnutrition and even death (El-Taweed 2015). And because this parasite is found in domesticated animals, there is a significant zoonotic transmission potential (Thompson. 2000). A calf can shed 105 to 106 cysts per gram of feces, and re-infection can occur with ingesting as few as 10 cysts. As the Giardia cysts survive well in water there is a potential f or contamination of untreated water supply as well (Thompson 2000 and Watkins and Eckmann 2014). There is no vaccine available for Giardia, so the treatment of the disease involves drug therapy, like the antibiotic metronidazole, a 5-nitroimadazole class drug (Watkins and Eckmann 2014 and Hart et al. 2017). Other drugs of this class are also used to treat giardiasis with varying degrees of success. However, like many antibiotics some drug resistance has been found (Watkins and Eckmann 2014). Several studies demonstrate Giardia spp. resistance to the 5-nitroimadazole class of drugs, including one that recorded 22% of patients in a clinic in Spain receiving treatment for giardiasis did not respond to metronidazole (El-Taweed 2015). Perhaps contributing to the problem of emerging drug resistance, are the undesirable side effects of common antiprotozoal drugs. Some of these side effects include intestinal discomfort, flatulence, nausea, vomiting, and the metallic taste of the drugs (Sahib et al. 2014). It is human nature to stop using a drug with these side effects as soon as it seems to be working, and this leads to the potential for an increase in 5-nitroimidazole drug resistance over time. Also, the use of the 5-nitromadazole class drugs at lower doses for treating gingivitis and pre-surgical colorectal cases, may allow for the growth of drug-resistant forms of Giardia (El-Taweed et al. 2015). Research into how Giardia become resistant to metronidazole and the active components of other successful drugs is important to the success of treating giardiasis in humans and animals. The investigations into different drugs and herbal remedies involve identifying the mode-of-action, how the active component is effectiv e against this protozoan in both trophozoites and cyst form (Galeh et al. 2016). As an alternative to metronidazole, older antibiotic drugs, new antibiotic drugs and plant extracts and essential oils are being considered by many researchers. Newer drugs are being considered to overcome Giardia resistance like auranofin, a drug currently prescribed for rheumatoid arthritis (Watkins and Eckmann 2014.). Researchers are also considering plants and plant extracts for a new anti-giardia agent. These extracts have been used in traditional medicine to treat diarrhea in places in South America, India, Iran, and Turkey where Giardia is endemic (Watkins and Eckmann 2014). Research has been done investigating compounds from garlic (Mikaili et al. 2014), ginger and cinnamon (Mahmoud et al. 2014), pomegranate (Al-Megrin 2017), and native plants from Brazil (Martins et al. 2015), the Yucatan (Sergio et al. 2005) and their effectiveness against Giardia. Identifying the compounds in the plants that are most effective against the protozoa will provide another option for treatment of giardiasis. Drug Therapies As previously mentioned, the number of cases of Metronidazole-resistant giardiasis is growing. Other 5-nitroimadazole and nitro-class drugs have been tested against Giardia like nitazoxanide and furazolidone (Watkins and Eckmann 2014). These drugs work by reducing the nitrogen group on the drug compounds to activate toxic free radicals. The advantages of the new drugs are shorter length of treatment and reduced cellular damage to the liver and kidneys (Jarrad et al 2016). Side effects are seen in the use of these drugs, as in the case of furazolidone, where some hemolysis was observed in some patients (Watkins and Eckmann 2014) and in 5-nitroimadazole drugs side effects like nausea, vomiting and headaches are reported (Jarrad et al. 2016). When developing new drug treatments, researchers investigate how the parasite is developing resistance to current treatments. In the case of 5-nitroimodazole drugs, the potency of a substance against Giardia species is due to the activation of the drug by an enzyme pyruvate ferredoxin oxidoreductase (PFOR). The drugs nitro group is reduced by the protozoans PFOR enzyme, producing toxic free radicals which bond to target molecules in the microbe, inactivating them and killing the parasite (Watkins and Eckmann 2014). The resistant protozoans have down-regulated the PFOR enzyme (Jarrad et al. 2016 and Galeh et al. 2016). To treat giardiasis, research has focused on this nitro group and the formation of toxic free radicals. Other drugs are being developed that incorporate a benzene ring, instead of (or in addition to) the nitro groups. These drugs act on the Giardia cellular vesicles, causing swelling, and are more effective than nitazoxanide and metronidazole (Watkins and Eckmann 2014) . Not all research has resulted in support for the development of new drugs in the 5-nitromiadazole class. In a study conducted in Iran, researchers tested the theory in human clinical studies, utilizing PCR to identify genetic mutations that appeared in metronidazole-resistant Giardia lamblia. In the metronidazole-resistant G. lamblia, the protozoa did not show down regulation of PFOR and it is suspected that other predisposing factors were responsible for the drugs ineffectiveness(Galeh et al. 2016). Further research is being done to test the new drugs like nitroimidazole and furazolidone for cytotoxicity towards human liver, kidney, and intestinal cells (Watkins and Eckmann 2014). These side effects can be serious in immune-compromised subjects and children. Older antibiotic drugs like albendazole and mebendazole, benzimidazole class drugs, have been shown to be effective against Giardia as well. These drugs are currently used to treat roundworm infections. The benzimidazole class drugs act by binding to tubulin and interfering with the protozoan cytoskeleton (Watkins and Eckmann, 2014). Research into the effectiveness of metronidazole and albendazole in mice showed that some Giardia isolates developed resistance to one or the other drug and in some cases both drugs (Lemà ©e et al. 2000). In the case of albendazole, some Giardia duodenalis resistance developed in a mouse model (Lemà ©e et al. 2000). In another study in Bolivia when albendazole was used to reduce the hookworm infection, the number of Giardia infections increased showing some (Watkins and Eckmann 2014). Drug research of existing drug libraries has also revealed some drugs that previously were not used as antimicrobials are effective against Giardia. A drug used for rheumatoid arthritis, auranofin, inhibits the growth of metronidazole-resistant Giardia. It works by inhibiting the thioredoxin-glutathione reductase enzyme (Watkins and Eckmann 2014). A drug used for obesity treatment, orlistat, which is poorly absorbed, is active in the intestine. Orlistat works by inhibiting lipases in Giardia isolates, preventing lipid metabolism (Watkins and Eckmann 2014). Ginger and Cinnamon Current research into metronidazole-resistant Giardia infections has gone beyond investigating new drugs or existing drug libraries. Diarrheal treatments around the world have shown promise in providing avenues for new giardiasis therapies and treatments. Some of this research involves the investigation into anti-nausea spices, ginger and cinnamon. Research has been conducted using ginger extracts in both in vivo and in vitro studies. In an in vitro study (Abdel-Hafeez et al. 2016), a comparison was made between gingers and nitazoxanides effectiveness against Giardia lamblia trophozoites. Ginger was chosen to contrast with the drug because of its historical use as an anti-nausea and anti-diarrheal treatment. Ginger extract is an antioxidant with alkaloids, saponins, tannins, and flavonoids. It is suspected that either the antioxidant or flavonoids have a negative effect on the trophozoites (Mahmoud et al. 2014). A study investigated curcumin, an antioxidant, also found in Zingiber officinale and other pungent spices (Perrez-Arriaga et al. 2006) showed that in the presence of curcumin at concentrations similar to metronidazole, significant swelling was seen in the Giardia trophozoites, indicating possible cell membrane interference (Perrez-Arriaga et al. 2006). In the research conducted by Abdel-Hafeez et al. (2016), cultured fecal samples treated with ginger extract at 20mg/mL resulted in similar reduction of the number of viable trophozoites in the culture as nitazoxanide. The findings were based on counts of viable trophozoites (pear-shaped, mobile, and non-refractory quality) under a light microscope. Verification of findings may use in vivo studies with mice or rats, and improved counting and staining techniques are indicated for future research. Meanwhile, ginger continues to be used for a variety of intestinal infections in Thailand, India, and Egypt (Abdel-Hafeez et al. 2016). In the in vivo study by Mahmoud, et al (2014)., cinnamon was also evaluated against Giardia trophozoites and cysts. As stated previously, the cyst is found in fecal samples as a transmissible form. The researchers This study involved using Giardia lamblia cyst infected rats and measured doses of ginger at 10 and 20 mg/kg/day and cinnamon at 10 and 20 mg/kg/day. As Perrez-Arriaga et al. (2006) previously researched, active compounds in ginger may affect the protozoans cell membrane. In another study, Proanthocyanidins were identified as an active compound in cinnamon (Williams et al. 2015). Proanthocyanidins, also found in berries, disrupt protozoans adhesive ability which is necessary for the trophozoite to maintain its position in the intestine (Anthony et al. 2007). In the Mahmoud study (2014) the rats were euthanized and their intestines washed for a measurement of trophozoites and to determine intestinal damage (Anthony et al. 2007). Their stools were also collected for three day s prior to euthanasia to perform a count of cysts excreted (Mahmoud et al. 2014). According to the results of this study, cinnamon given to the rats at the 20 mg/kg dose resulted in a 100% reduction in the number of cysts found in their fecals, and a 34% reduction in the number of trophozoites. When rats were given a dose of 20mg/kg of ginger the number of cysts found in their stool was reduced by 90.1% and the number of trophozoites in the intestinal wash was reduced by 75.45%. So, the cinnamon was more active against cysts and the ginger was more active against the trophozoites in the rats (Mahmoud et al. 2014). The study also utilized electron microscopy to count and identify Giardia cysts and trophozoites. By utilizing this technology, and the researchers were able to show that not only was the infection reduced with cinnamon, but the intestinal mucosa was healthier in the samples taken as compared to the ginger-dosed rats (Mahmoud et al. 2014). This study, however did not utili ze a positive control group to measure the difference (if any) between using ginger and cinnamon extracts compared with using metronidazole or other drug treatment for giardiasis. Additional research may determine whether the intestinal mucosa would improve, with the drug treatment as occurred in the study with cinnamon and ginger (Mahmoud et al. 2014). Garlic and Shallot One of the most promising and researched herbal extract is allicin, a component of plants in the garlic and onion family. Garlic and shallot plants have been used in traditional medicine in various parts of the world for hundreds of years (Mikaili et al. 2013). Sulfur-based components like allicin (diallyl dithiosulfinate), diallyl disulfide, and S-allylcystein of these plants are of interest to research for use in pharmacological studies (Mikaili et al. 2013). In an in vitro study investigating whole garlic extract (Harris et al. 2000), garlic was shown to be effective against Giardia intestinalis at a concentration of 0.3mg/mL. The researchers went on to examine how the compounds in garlic were acting on the Giardia and whether allicin was the compound of interest. Allicin has a very short half-life in vivo, but the thiosulfates that result from its breakdown are bioavailable longer to act against Giardia trophozoites (Harris et al. 2000). In this study the researchers investigated the anti-parasitic activity of these compounds, and they showed that diallyl disulphide was particularly effective in reducing the number of trophozoites. Another component, allyl alcohol, damaged the trophozoites by causing cellular swelling and immobility (Harris et al. 2000). In another study focusing on diallyl trisulfide (DAT) from garlic, a concentration of 300 ug/mL was effective against Giardia lamblia (Lun et al. 1994). The researchers used an in vitro test to determine the IC50 for DAT, and the result was 8.5-14 ug/mL, using the same tests that determined the IC50 of metronidazole. The use of DAT in China for treatment of other parasitic infections is not uncommon (Lun et al. 1994), but it will be necessary to determine how DAT is effective against the parasite in vivo in future research. One avenue that research may pursue is in studying how DAT affects tubulin (Hosono et al. 2005), which would indicate that this substance has a similar effect as the benzimidazole drugs like albendazole. Further research into obtaining effective concentrations of these components of garlic and onions is necessary. Herbal Extracts Other herbal extracts have been investigated for their biologically active components and effectiveness as a treatment for giardiasis. Three of these show promise in recent studies. Peppermint (Mentha x piperta L.) is used as an herbal remedy for stomach discomfort (Vidal et al. 2007). Dill is also used in some areas of the world to treat children with diarrhea (Sahib et al. 2014). Pomegranate peel contains some substances that prove active against Giardia (Al-Megrin 2016). Mentha x piperta (peppermint) is known to have a relaxation effect on gastrointestinal smooth muscle, and this is suspected to be the result of the menthol affecting calcium channels (Kiefer et al. 2008). In one study methanolic extract from Mentha x piperta was tested against Giardia lamblia (Vidal et al. 2007). This study measures IC50, which is the calculation of the amount of a substance necessary to inhibit or kill one-half of the microbes. The IC50 after 48 hours of exposure was 0.8 ug/mL, similar to the IC50 of metronidazole and furazalidone after 24 hours (Vidal et al. 2007). The study tested different concentrations of the dichloromethane (DCM) from Mentha x piperta and found that a dose of 100 ug/mL after 48 hours almost eliminated the presence of trophozoites in the culture media (Vidal et al. 2007). The study also examined how DCM was altering the morphology of trophozoites utilizing electron microscopy, and found changes to plasma membranes (Vidal et al. 2007). This sugg ests the need for further research into why the protozoal membranes were altered, what biologically active components of peppermint were involved, and whether this alteration would also affect intestinal cells in mammals (measuring potential toxicity). In a study that researched the extracts from the Dill plant (Anethum graveolens), researchers conducted a clinical trial with children Giardia trophozoites and cysts, or if the dill acted on the muscle cells in the intestine, reducing smooth muscle contraction. Further research needs to be conducted into these issues. Pomegranate peel extract was also tested for anti-Giardia activity in another study (Al-Megrin 2016). Researchers studied mice that were infected with the Giardia cysts, and given an extract of pomegranate peel daily. Then the number of cysts produced in the mouse stool and the antigen presence for Giardia were counted and measured respectively. There was a reduction in the number of cysts counted in the groups of mice that had received the pomegranate, however there was also a natural reduction in the number of cysts in the studys control group (Al-Megrin 2016). The researchers also reported that the rate of detection of the Giardia antigen in the groups that were treated was significantly (P Native Plants Ethnopharmacology is becoming one method for identifying plant-based sources for new pharmacological treatments. Ethnopharmacology studies involve interviewing people who are native to specific areas to identify historical and current plant species used to treat disease. In the case of Giardia treatment, researchers identified diarrhea as the key symptom in 90% of human cases (Neiva et al. 2014). Although people reporting to clinics or hospitals with diarrhea did not necessarily identify causative agents, in some cases they were self-treating with plants from the area or from their own gardens (Neiva, et al. 2014). The identification of plants used by people suffering from diarrhea allowed researchers to focus on specific plant species in anti-giardiasis studies. In one study by Neiva et al. (2014) the researchers focused on an area around Sao Luis, Brazil. From interviewing and collecting plant samples that people were using to treat diarrhea and dysentery symptoms, the researchers identified five potential plants to test for anti-Giardia effectiveness. The researchers also identified the part of the plants and the preparation of the plants used for treatment of diarrhea by these patients of a healthcare facility and private specialty institution (Neiva et al. 2014). The five species of plants selected to investigate were Anacardium occidentale L., Chenopodium ambrosioides L., Passiflora edulis Sims., Psiddiumguajava L., and Stachytarpheta cayennesis (Rich) Vahl. (Neiva et al. 2014). It was found that all the plants had some giardicidal activity, but Passiflora was most effective at IC50 In another similar ethnopharmacology study, researchers investigated plants native to the Yucatan peninsula in Mexico that were used to treat diarrhea (Paraza-Sanchez et al. 2005). This study was conducted in vitro using 10 methanol extracts from native plants. In this study Tridax procumens as a whole plant was used (air-dried and powdered into methanol, then evaporated, and added to DMSO) (Paraza-Sanchez et al. 2005). The researchers identified from other studies that the plant contains hydrocarbons, fatty acids, flavonoids, bis-bithiophene. Flavonoids may contain polyphenols and inhibit Giardia from adhering to the intestinal wall (Anthony et al. 2007) In other plants tested, C. dentata, D. cahagenesis, and B. cressifolia have not had their chemical components analyzed, although they all had giardicidal activity (Paraza-Sanchez et al. 2005). It is unknown at this time why these native plants are effective against Giardia spp. (Paraza-Sanchez et al. 2005). Research has been conducted on the Rubus liebmanii medicinal plant native to Mexico. The antiprotozoal active compounds were identified as epicatechin and catechin (polyphenols), Nigaichigoside F1, beta-sitosterol, squalene, and 3,4 hydroxybenzoic acid (Jimà ©nez-Arellanes et al. 2012). In this study, extracts from the plant were fractionated to identify specific compounds, an extract of R. liebomanii was tested against G. lamblia with a negative control and a metronidazole infused positive control, and the research continued using guinea pigs and mice as test subjects. The results indicated that the Nigaichigoside F1 had an IC50 of 2.17 ug/mL as compared with metronidazole which had an IC50 of 0.5 ug/mL in cultures of G. lamblia (Jimà ©nez-Arellanes et al. 2012). When the potential toxicity of the plant was tested in male rats, the pure extract of R. liebmanii was not toxic, even at 1000mg/kg dosages (Jimà ©nez-Arellanes et al. 2012). Further research into these plants may involv e identifying how the active components are working against the protozoans and identify more effective treatments, which will need to be tested in vivo. Solanum lycoparum is also a native plant of Brazil. In research published in 2015 (Gilmarcio et al. 2015), this native species was investigated for its anti-Giardia potential. The fruit of this plant is used in traditional medicine (Gilmarcio et al. 2015). Two glycoalkaloids, solamargin (Sg) and solasonine (Sn) have been identified as having potential as anti-Giardia treatments (Gilmarcio et al. 2015). Both compounds were effective against Giardia lamblia, with Sg having an IC50 of 120.3 ug/mL and Sn having an IC50 of 103.7 ug/mL. However, when both compounds were mixed as they would be in the fruit of S. lycoparum, their IC50 was 13.23 ug/mL, much lower (Gilmarcio et al. 2015). This demonstrates a synergistic effect of the compounds. The researchers also used an index of selectivity calculation to measure effectiveness of the compound as compared to toxicity against macrophages, and the combined glycoalkaloids had a relatively high index (Gilmarcio et al. 2015). This index was neces sary because glycoalkaloids can be toxic. In vitro studies of the combined Sn+Sg treatment would provide additional research opportunities and determine the toxic effects of the glycoalkaloid while treating Giardia lamblia. Glycoalkaloids affect permeability of mammalian intestinal cells (Gee et al. 1996), however the glycoalkaloids found and studied from the S. lycoparum are not the most toxic. It is likely; however, no research could be found in the current literature searches, that the effect of glycoalkaloids on the Giardia trophozoites cell membrane did cause cellular swelling and changes to the vesicles and flagella. Essential Oils Clove oil, an essential oil from Syzgium aromaticum, has been used to treat digestive disorders and diarrhea (Machado et al. 2011). Research into essential oils has shown they are effective against many bacterial and fungal infections, but little research has been done to discover how the oil works (Machado et al. 2011). Eugenol is a major of several essential oils including S. aromaticum, and in this research the eugenol comprised 85% of the essential oil tested (Machado et al. 2011).In a study testing the effect of clove oil and eugenol on Giardia lamblia it was shown that S. aromaticum had an IC50 value of 134 ug/mL and eugenol had an IC50 value of 101 ug/mL (Machado et al. 2011). The study also utilized scanning and transmission electron microscopy to measure morphological changes in the Giardia that were incubated with the S. aromaticum essential oil. It was observed that the adherence of the Giardia was inhibited in the presence of eugenol (Machado et al. 2011). Giardia normall y attach to the intestinal wall to maintain position, obtain nutrients, and reproduce. The essential oil contained eugenol, and although it affected adherence, it did not cause the Giardia trophozoites to lyse, so the results in this study indicated that other components of the S. aromaticum oil were responsible for the cell death (Machado et al. 2011). Other essential oils are used to treat digestive issues. One, from Ocimum basilicum of the basil family, was studied for its anti-Giardia effects (de Almeida et al. 2007). In this study the researchers again isolated components of the essential oil and tested for antigiardial activity (de Almeida et al. 2007). This study also investigated eugenol as one of those components, and found the eugenol was effective against the Giardia trophozoites (de Almeida et al. 2007). The study included testing the linalool, which makes up 69.33% of the essential oil in addition to eugenol. Linalool was shown to be even more effective at reducing the number of viable Giardia lamblia trophozoites (de Almeida et al. 2007). To verify potential toxicity of the essential oil and its components, the researchers tested mouse macrophages in the same concentrations of Ocimum basilicum, eugenol and linalool and found that there was little to no effect on the cells (de Almeida et al. 2007). The researchers also identified an inhibitory effect of the oil and it components to a group of cysteine peptidases enzymes that are commonly found in these protozoans (de Almeida et al. 2007). The inhibition of cysteine peptidases has been shown to have a lethal effect on trophozoites of another protozoal species, Entamoeba histolytica (Ankri et al. 1997). Ozone In an interesting study (Boland-Nazar et al. 2016), olive oil injected with ozone was tested as a treatment for giardiasis. In an in vitro study, the tubes of Giardia were combined with different concentrations of ozonated olive oil, and this proved effective against Giardia cysts after 100 hours of incubation (Boland-Nazar et al. 2016). It is suspected by the researchers that the extra oxygen atom acts a free radical, like the immunological response of macrophages and neutrophils (Boland-Nazar et al. 2016). Olive oil is effective at stabilizing a delivery system for ozone without losing its durability (Boland-Nazar et al. 2016), and the higher the concentration of ozone in the oil, the more effective the treatment is against Giardia cysts. The researchers suggest conducting an in vivo study with this substance to verify their hypothesis (Boland-Nazar et al. 2016). Discussion Research into treating giardiasis will continue as standard treatments like metronidazole go up against greater drug resistance. The mode of action of different therapies has been investigated and includes inhibiting PFOR, cysteine proteinases, inhibiting adherence (Anthony et al. 2007), tubulin and cytoskeleton interference, and cell membrane interference. Table 1 shows some of the different treatments dosage requirements and active compounds. The 5nitroimadazole drugs are the most commonly prescribed treatments for giardiasis world-wide. New drugs are being developed from within this class, altering the nitro-group or adding benzene rings to the molecules to improve effectiveness considering growing metronidazole resistance (Watkins and Eckmann 2014). Other drugs that have been prescribed for anti-parasitic treatment or other purposes entirely are also being investigated. This includes anthelminthic drugs as well as drugs that were initially developed to treat obesity and rheumatoid arthritis (Watkins and Eckmann 2014). Finally, herbal, spice, and plant-based extracts are being investigated for their antiprotozoal activity. Although Table1 does not show an IC50 for each of the compounds discussed in this paper, it does highlight the active components. Table 1: Effectiveness of different substances in inhibiting Giardia IC50 Active compound Reference Metronidazole 0.8 ug/mL 5-nitroimadazole Jarrad et al. 2016, Watkins and Eckmann, 2014, Vidal et al 2007 Albendazole 52.4 ug/mL Benzimidazole Jarrad et al. 2016, Watkins and Eckmann, 2014, Lemee et al. 2000 Furazolidone 0.65 ug/mL 5-nitrofurans Jarrad et al. 2016, Watkins and Eckmann, 2014, Vidal et al 2007 Garlic 14 ug/mL Diallyl trisulfide Lun